FP1644GB VRAM minimum

Mistralai Mixtral 8x22b Instruct V0 1 FP16 VRAM Requirements

This page answers Mistralai Mixtral 8x22b Instruct V0 1 fp16 queries with explicit calculations from our model requirement dataset and compatibility speed table.

Short answer

Direct requirement summary for Mistralai Mixtral 8x22b Instruct V0 1 FP16

Short answer: Mistralai Mixtral 8x22b Instruct V0 1 typically needs around 44GB VRAM at FP16, and 53GB is safer for smoother usage.

Minimum VRAM

44GB

Recommended VRAM

53GB

Target quantization

FP16

Requirement Snapshot

Current quantization-specific requirement breakdown

Selected quantizationFP16

Minimum VRAM44GB

Q4 baseline11GB

Q8 baseline22GB

FP16 baseline44GB

Methodology

No hand-wavy numbers

Exact FP16 requirement from model requirement data.

Throughput data below uses available compatibility measurements/estimates and is sorted by tokens per second for this model.

Need general guidance? Review full methodology.

Next steps for this requirement

AMD Instinct MI300X

Check full compatibility details and speed context for this model.

Can AMD Instinct MI300X run Mistralai Mixtral 8x22b Instruct V0 1? →Buy options for AMD Instinct MI300X →

NVIDIA H200 SXM 141GB

Check full compatibility details and speed context for this model.

Can NVIDIA H200 SXM 141GB run Mistralai Mixtral 8x22b Instruct V0 1? →Buy options for NVIDIA H200 SXM 141GB →

NVIDIA H100 SXM5 80GB

Check full compatibility details and speed context for this model.

Can NVIDIA H100 SXM5 80GB run Mistralai Mixtral 8x22b Instruct V0 1? →Buy options for NVIDIA H100 SXM5 80GB →

Need GPU recommendations?

Compare curated best GPU guides by budget and workload.

Browse best GPU guides →

Need a complete build?

Use proven local AI build recipes if you are planning a fresh hardware setup.

Browse local AI builds →

Prefer prebuilt systems?

Compare ready-to-buy systems if you want faster deployment.

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Compare other quantization tiers for Mistralai Mixtral 8x22b Instruct V0 1

Q4 requirements Q4_K_M requirements Q5_K_M requirements Q8 requirements

Best GPUs for Mistralai Mixtral 8x22b Instruct V0 1 (FP16)

GPU	VRAM	Quantization	Speed	Compatibility	Buy
AMD Instinct MI300X	192GB	FP16	207 tok/s	View full compatibility	Buy options
NVIDIA H200 SXM 141GB	141GB	FP16	187 tok/s	View full compatibility	Buy options
NVIDIA H100 SXM5 80GB	80GB	FP16	135 tok/s	View full compatibility	Buy options
AMD Instinct MI250X	128GB	FP16	130 tok/s	View full compatibility	Buy options
NVIDIA H100 PCIe 80GB	80GB	FP16	85 tok/s	View full compatibility	Buy options
RTX 5090	32GB	FP16	81 tok/s	View full compatibility	Buy options
NVIDIA A100 80GB SXM4	80GB	FP16	79 tok/s	View full compatibility	Buy options
AMD Instinct MI210	64GB	FP16	65 tok/s	View full compatibility	Buy options
NVIDIA A100 40GB PCIe	40GB	FP16	62 tok/s	View full compatibility	Buy options
RTX 4090	24GB	FP16	49 tok/s	View full compatibility	Buy options
NVIDIA RTX 6000 Ada	48GB	FP16	49 tok/s	View full compatibility	Buy options
NVIDIA L40	48GB	FP16	45 tok/s	View full compatibility	Buy options

Back to Mistralai Mixtral 8x22b Instruct V0 1 model page Full hardware requirements Best GPU guides Prebuilt systems Local AI build guides

VRAM requirements FAQ

How much VRAM does Mistralai Mixtral 8x22b Instruct V0 1 need at FP16?

Mistralai Mixtral 8x22b Instruct V0 1 at FP16 is estimated to require about 44GB VRAM minimum, with 53GB recommended for smoother operation.

Which GPUs can run Mistralai Mixtral 8x22b Instruct V0 1 FP16?

Start with AMD Instinct MI300X, NVIDIA H200 SXM 141GB, NVIDIA H100 SXM5 80GB and review each compatibility page for full speed and fit details.

Should I use FP16 or a different quantization for Mistralai Mixtral 8x22b Instruct V0 1?

FP16 is a balance point between memory usage and quality. If your GPU is below 44GB, consider lower-bit quantization; if you have extra VRAM, compare Q8/FP16 options for quality-sensitive workloads.

FP1644GB VRAM minimum

Mistralai Mixtral 8x22b Instruct V0 1 FP16 VRAM Requirements

This page answers Mistralai Mixtral 8x22b Instruct V0 1 fp16 queries with explicit calculations from our model requirement dataset and compatibility speed table.

Short answer

Direct requirement summary for Mistralai Mixtral 8x22b Instruct V0 1 FP16

Short answer: Mistralai Mixtral 8x22b Instruct V0 1 typically needs around 44GB VRAM at FP16, and 53GB is safer for smoother usage.

Minimum VRAM

44GB

Recommended VRAM

53GB

Target quantization

FP16

Requirement Snapshot

Current quantization-specific requirement breakdown

Selected quantizationFP16

Minimum VRAM44GB

Q4 baseline11GB

Q8 baseline22GB

FP16 baseline44GB

Methodology

No hand-wavy numbers

Exact FP16 requirement from model requirement data.

Throughput data below uses available compatibility measurements/estimates and is sorted by tokens per second for this model.

Need general guidance? Review full methodology.

Next steps for this requirement

AMD Instinct MI300X

Check full compatibility details and speed context for this model.

Can AMD Instinct MI300X run Mistralai Mixtral 8x22b Instruct V0 1? →Buy options for AMD Instinct MI300X →

NVIDIA H200 SXM 141GB

Check full compatibility details and speed context for this model.

Can NVIDIA H200 SXM 141GB run Mistralai Mixtral 8x22b Instruct V0 1? →Buy options for NVIDIA H200 SXM 141GB →

NVIDIA H100 SXM5 80GB

Check full compatibility details and speed context for this model.

Can NVIDIA H100 SXM5 80GB run Mistralai Mixtral 8x22b Instruct V0 1? →Buy options for NVIDIA H100 SXM5 80GB →

Need GPU recommendations?

Compare curated best GPU guides by budget and workload.

Browse best GPU guides →

Need a complete build?

Use proven local AI build recipes if you are planning a fresh hardware setup.

Browse local AI builds →

Prefer prebuilt systems?

Compare ready-to-buy systems if you want faster deployment.

Compare prebuilt systems →

Compare other quantization tiers for Mistralai Mixtral 8x22b Instruct V0 1

Q4 requirements Q4_K_M requirements Q5_K_M requirements Q8 requirements

Best GPUs for Mistralai Mixtral 8x22b Instruct V0 1 (FP16)

GPU	VRAM	Quantization	Speed	Compatibility	Buy
AMD Instinct MI300X	192GB	FP16	207 tok/s	View full compatibility	Buy options
NVIDIA H200 SXM 141GB	141GB	FP16	187 tok/s	View full compatibility	Buy options
NVIDIA H100 SXM5 80GB	80GB	FP16	135 tok/s	View full compatibility	Buy options
AMD Instinct MI250X	128GB	FP16	130 tok/s	View full compatibility	Buy options
NVIDIA H100 PCIe 80GB	80GB	FP16	85 tok/s	View full compatibility	Buy options
RTX 5090	32GB	FP16	81 tok/s	View full compatibility	Buy options
NVIDIA A100 80GB SXM4	80GB	FP16	79 tok/s	View full compatibility	Buy options
AMD Instinct MI210	64GB	FP16	65 tok/s	View full compatibility	Buy options
NVIDIA A100 40GB PCIe	40GB	FP16	62 tok/s	View full compatibility	Buy options
RTX 4090	24GB	FP16	49 tok/s	View full compatibility	Buy options
NVIDIA RTX 6000 Ada	48GB	FP16	49 tok/s	View full compatibility	Buy options
NVIDIA L40	48GB	FP16	45 tok/s	View full compatibility	Buy options

Back to Mistralai Mixtral 8x22b Instruct V0 1 model page Full hardware requirements Best GPU guides Prebuilt systems Local AI build guides

VRAM requirements FAQ

How much VRAM does Mistralai Mixtral 8x22b Instruct V0 1 need at FP16?

Mistralai Mixtral 8x22b Instruct V0 1 at FP16 is estimated to require about 44GB VRAM minimum, with 53GB recommended for smoother operation.

Which GPUs can run Mistralai Mixtral 8x22b Instruct V0 1 FP16?

Start with AMD Instinct MI300X, NVIDIA H200 SXM 141GB, NVIDIA H100 SXM5 80GB and review each compatibility page for full speed and fit details.

Should I use FP16 or a different quantization for Mistralai Mixtral 8x22b Instruct V0 1?

FP16 is a balance point between memory usage and quality. If your GPU is below 44GB, consider lower-bit quantization; if you have extra VRAM, compare Q8/FP16 options for quality-sensitive workloads.