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Can RTX 4090 run Mistralai Mistral Small Instruct 2409?

Mistralai Mistral Small Instruct 2409 speed on RTX 4090 and quantization-level VRAM fit.

Runs Q424GB VRAM availableRequires 20GB+

RTX 4090 meets the minimum VRAM requirement for Q4 inference of Mistralai Mistral Small Instruct 2409. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for RTX 4090Best GPU guidesCompare prebuilt systems
Short answer: RTX 4090 can run Mistralai Mistral Small Instruct 2409 at Q4 with an estimated 63 tok/s.
Estimated speed
63 tok/s
VRAM needed
20GB
VRAM headroom
+4GB

What this means for you

RTX 4090 can run Mistralai Mistral Small Instruct 2409 with Q4 quantization. At approximately 63 tokens/second, you can expect Good speed - acceptable for interactive use.

You have 4GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q420GB24GB63.00 tok/s✅ Fits comfortably
Q840GB24GB44.10 tok/s❌ Not recommended
FP1680GB24GB23.94 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
267.14 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Mistralai Mistral Small Instruct 2409 on AMD Instinct MI300X
NVIDIA H200 SXM 141GB
141GB
241.24 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Mistralai Mistral Small Instruct 2409 on NVIDIA H200 SXM 141GB
NVIDIA H100 SXM5 80GB
80GB
173.27 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Mistralai Mistral Small Instruct 2409 on NVIDIA H100 SXM5 80GB
AMD Instinct MI250X
128GB
167.14 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Mistralai Mistral Small Instruct 2409 on AMD Instinct MI250X
NVIDIA H100 PCIe 80GB
80GB
109.99 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Mistralai Mistral Small Instruct 2409 on NVIDIA H100 PCIe 80GB

Compare purchase paths

Direct GPU buy options

Check current pricing links for RTX 4090 and similar cards.

Open RTX 4090 buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

More questions

RTX 4090 buy options & pricingFull guide for Mistralai Mistral Small Instruct 2409Best GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksMistralai Mistral Small Instruct 2409 Q4 requirementsMistralai Mistral Small Instruct 2409 Q4_K_M requirementsCan AMD Instinct MI300X run Mistralai Mistral Small Instruct 2409?Can NVIDIA H200 SXM 141GB run Mistralai Mistral Small Instruct 2409?Can NVIDIA H100 SXM5 80GB run Mistralai Mistral Small Instruct 2409?

Compatibility FAQ

Can RTX 4090 run Mistralai Mistral Small Instruct 2409?

RTX 4090 can run Mistralai Mistral Small Instruct 2409 at Q4 with an estimated 63 tok/s.

How much VRAM is needed for Mistralai Mistral Small Instruct 2409 on RTX 4090?

Q4 inference is estimated to need about 20GB VRAM on this page, while RTX 4090 has 24GB available.

What if RTX 4090 is not enough for Mistralai Mistral Small Instruct 2409?

If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.