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GPUs for AI Models: Benchmarks & Specs

Can AMD Instinct MI250X run mistralai/Mistral-Small-Instruct-2409?

Runs Q4128GB VRAM availableRequires 11GB+

AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of mistralai/Mistral-Small-Instruct-2409. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Quantization breakdown

Quantization	VRAM needed	VRAM available	Estimated speed	Verdict
Q4	11GB	128GB	284.76 tok/s	✅ Fits comfortably
Q8	23GB	128GB	165.85 tok/s	✅ Fits comfortably
FP16	46GB	128GB	109.33 tok/s	✅ Fits comfortably

Suitable alternatives

AMD Instinct MI300X

192GB

442.66 tok/s

Price: —

NVIDIA H200 SXM 141GB

141GB

397.86 tok/s

Price: —

AMD Instinct MI300X

192GB

More questions

AMD Instinct MI250X specs & pricing Full guide for mistralai/Mistral-Small-Instruct-2409