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Can NVIDIA L40S run Qwen/Qwen2.5-Math-72B-Instruct?

Runs Q448GB VRAM availableRequires 36GB+

NVIDIA L40S meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-Math-72B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

NVIDIA L40S can run Qwen/Qwen2.5-Math-72B-Instruct with Q4 quantization. At approximately 34 tokens/second, you can expect Moderate speed - useful for batch processing.

You have 12GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q436GB48GB34.06 tok/s✅ Fits comfortably
Q871GB48GB21.08 tok/s❌ Not recommended
FP16142GB48GB12.58 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
148.25 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
130.01 tok/s
Price: —
AMD Instinct MI250X
128GB
105.02 tok/s
Price: —
AMD Instinct MI300X
192GB
100.63 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
92.01 tok/s
Price: —

More questions

NVIDIA L40S specs & pricingFull guide for Qwen/Qwen2.5-Math-72B-InstructQwen/Qwen2.5-Math-72B-Instruct speed on NVIDIA L40SQwen/Qwen2.5-Math-72B-Instruct Q4 requirements