NVIDIA H100 PCIe 80GB meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-Math-72B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
NVIDIA H100 PCIe 80GB can run Qwen/Qwen2.5-Math-72B-Instruct with Q4 quantization. At approximately 68 tokens/second, you can expect Good speed - acceptable for interactive use.
You have 44GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 36GB | 80GB | 68.34 tok/s | ✅ Fits comfortably |
| Q8 | 71GB | 80GB | 42.51 tok/s | ✅ Fits comfortably |
| FP16 | 142GB | 80GB | 24.55 tok/s | ❌ Not recommended |