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GPUs for AI Models: Benchmarks & Specs

Can AMD Instinct MI250X run Qwen/Qwen2.5-Math-72B-Instruct?

Runs Q4128GB VRAM availableRequires 36GB+

AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-Math-72B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Quantization breakdown

Quantization	VRAM needed	VRAM available	Estimated speed	Verdict
Q4	36GB	128GB	95.06 tok/s	✅ Fits comfortably
Q8	71GB	128GB	69.97 tok/s	✅ Fits comfortably
FP16	142GB	128GB	37.74 tok/s	❌ Not recommended

Suitable alternatives

AMD Instinct MI300X

192GB

166.12 tok/s

Price: —

NVIDIA H200 SXM 141GB

141GB

151.40 tok/s

Price: —

NVIDIA H100 SXM5 80GB

80GB

More questions

AMD Instinct MI250X specs & pricing Full guide for Qwen/Qwen2.5-Math-72B-Instruct