Apple M4 Pro meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-72B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
Apple M4 Pro can run Qwen/Qwen2.5-72B-Instruct with Q4 quantization. At approximately 8 tokens/second, you can expect Low speed - consider quantization or stronger GPU.
You have 29GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 35GB | 64GB | 7.80 tok/s | ✅ Fits comfortably |
| Q8 | 70GB | 64GB | 5.13 tok/s | ❌ Not recommended |
| FP16 | 141GB | 64GB | 2.74 tok/s | ❌ Not recommended |