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Can Apple M4 Max run Qwen Qwen2.5 72B Instruct?

Qwen Qwen2.5 72B Instruct speed on Apple M4 Max and quantization-level VRAM fit.

Runs Q4128GB VRAM availableRequires 36GB+

Apple M4 Max meets the minimum VRAM requirement for Q4 inference of Qwen Qwen2.5 72B Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Query match answer

Qwen qwen2.5 72b instruct speed on apple m4 max

Qwen Qwen2.5 72B Instruct runs on Apple M4 Max at about 15 tok/s at Q4 in our current compatibility dataset.

Based on 1,997 impressions tracked in Search Console.

Buy options for Apple M4 MaxBest GPU guidesCompare prebuilt systems
Short answer: Apple M4 Max can run Qwen Qwen2.5 72B Instruct at Q4 with an estimated 15 tok/s.
Estimated speed
15 tok/s
VRAM needed
36GB
VRAM headroom
+92GB

What this means for you

Apple M4 Max can run Qwen Qwen2.5 72B Instruct with Q4 quantization. At approximately 15 tokens/second, you can expect Basic speed - best for non-interactive tasks.

You have 92GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q436GB128GB14.65 tok/s✅ Fits comfortably
Q872GB128GB10.25 tok/s✅ Fits comfortably
FP16144GB128GB5.57 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
152.65 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Qwen Qwen2.5 72B Instruct on AMD Instinct MI300X
NVIDIA H200 SXM 141GB
141GB
137.85 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Qwen Qwen2.5 72B Instruct on NVIDIA H200 SXM 141GB
NVIDIA H100 SXM5 80GB
80GB
99.01 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Qwen Qwen2.5 72B Instruct on NVIDIA H100 SXM5 80GB
AMD Instinct MI250X
128GB
95.51 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Qwen Qwen2.5 72B Instruct on AMD Instinct MI250X
NVIDIA H100 PCIe 80GB
80GB
62.85 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Qwen Qwen2.5 72B Instruct on NVIDIA H100 PCIe 80GB

Compare purchase paths

Direct GPU buy options

Check current pricing links for Apple M4 Max and similar cards.

Open Apple M4 Max buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

Try before you buy

Rent cloud GPUs by the hour — no upfront hardware cost.

Vast.aiFrom $0.20/hr · Pay as you goRent GPU →RunPodFrom $0.30/hr · Secure cloudRent GPU →Lambda LabsFrom $0.50/hr · Enterprise-gradeRent GPU →

More questions

Apple M4 Max buy options & pricingFull guide for Qwen Qwen2.5 72B InstructBest GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksQwen Qwen2.5 72B Instruct Q4 requirementsQwen Qwen2.5 72B Instruct Q4_K_M requirementsCan AMD Instinct MI300X run Qwen Qwen2.5 72B Instruct?Can NVIDIA H200 SXM 141GB run Qwen Qwen2.5 72B Instruct?Can NVIDIA H100 SXM5 80GB run Qwen Qwen2.5 72B Instruct?

Compatibility FAQ

Can Apple M4 Max run Qwen Qwen2.5 72B Instruct?

Apple M4 Max can run Qwen Qwen2.5 72B Instruct at Q4 with an estimated 15 tok/s.

How much VRAM is needed for Qwen Qwen2.5 72B Instruct on Apple M4 Max?

Q4 inference is estimated to need about 36GB VRAM on this page, while Apple M4 Max has 128GB available.

What if Apple M4 Max is not enough for Qwen Qwen2.5 72B Instruct?

If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.