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GPUs for AI Models: Benchmarks & Specs

Can AMD Instinct MI300X run Qwen/Qwen2.5-72B-Instruct?

Runs Q4192GB VRAM availableRequires 35GB+

AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-72B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Quantization breakdown

Quantization	VRAM needed	VRAM available	Estimated speed	Verdict
Q4	35GB	192GB	152.05 tok/s	✅ Fits comfortably
Q8	70GB	192GB	96.67 tok/s	✅ Fits comfortably
FP16	141GB	192GB	57.13 tok/s	✅ Fits comfortably

Suitable alternatives

NVIDIA H200 SXM 141GB

141GB

141.11 tok/s

Price: —

NVIDIA H200 SXM 141GB

141GB

105.82 tok/s

Price: —

NVIDIA H100 SXM5 80GB

80GB

More questions

AMD Instinct MI300X specs & pricing Full guide for Qwen/Qwen2.5-72B-Instruct