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Can Apple M3 Pro run Qwen/Qwen2.5-72B-Instruct?

Runs Q436GB VRAM availableRequires 35GB+

Apple M3 Pro meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-72B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

Apple M3 Pro can run Qwen/Qwen2.5-72B-Instruct with Q4 quantization. At approximately 4 tokens/second, you can expect Low speed - consider quantization or stronger GPU.

VRAM usage will be very close to your GPU's limit. Consider closing other applications or using Q3 quantization for more margin.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q435GB36GB3.84 tok/s⚠️ Tight fit
Q870GB36GB2.65 tok/s❌ Not recommended
FP16141GB36GB1.54 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
153.28 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
126.76 tok/s
Price: —
AMD Instinct MI300X
192GB
107.35 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
99.80 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
98.56 tok/s
Price: —

More questions

Apple M3 Pro specs & pricingFull guide for Qwen/Qwen2.5-72B-InstructQwen/Qwen2.5-72B-Instruct speed on Apple M3 ProQwen/Qwen2.5-72B-Instruct Q4 requirements