Mistralai Mixtral 8x22b Instruct V0 1 speed on AMD Ryzen AI Max+ 395 and quantization-level VRAM fit.
AMD Ryzen AI Max+ 395 meets the minimum VRAM requirement for Q4 inference of Mistralai Mixtral 8x22b Instruct V0 1. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Ryzen AI Max+ 395 can run Mistralai Mixtral 8x22b Instruct V0 1 with Q4 quantization. At approximately 9 tokens/second, you can expect Low speed - consider quantization or stronger GPU.
You have 57GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 71GB | 128GB | 9.49 tok/s | ✅ Fits comfortably |
| Q8 | 141GB | 128GB | 6.64 tok/s | ❌ Not recommended |
| FP16 | 282GB | 128GB | 3.61 tok/s | ❌ Not recommended |
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AMD Ryzen AI Max+ 395 can run Mistralai Mixtral 8x22b Instruct V0 1 at Q4 with an estimated 9 tok/s.
Q4 inference is estimated to need about 71GB VRAM on this page, while AMD Ryzen AI Max+ 395 has 128GB available.
If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.