Qwen Qwen2.5 72B Instruct speed on AMD Radeon Pro W7900 and quantization-level VRAM fit.
AMD Radeon Pro W7900 meets the minimum VRAM requirement for Q4 inference of Qwen Qwen2.5 72B Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Radeon Pro W7900 can run Qwen Qwen2.5 72B Instruct with Q4 quantization. At approximately 29 tokens/second, you can expect Moderate speed - useful for batch processing.
You have 12GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 36GB | 48GB | 29.09 tok/s | ✅ Fits comfortably |
| Q8 | 72GB | 48GB | 20.36 tok/s | ❌ Not recommended |
| FP16 | 144GB | 48GB | 11.05 tok/s | ❌ Not recommended |
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AMD Radeon Pro W7900 can run Qwen Qwen2.5 72B Instruct at Q4 with an estimated 29 tok/s.
Q4 inference is estimated to need about 36GB VRAM on this page, while AMD Radeon Pro W7900 has 48GB available.
If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.