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Can RTX 4090 run Microsoft Phi 3 Medium 128K Instruct?

Microsoft Phi 3 Medium 128K Instruct speed on RTX 4090 and quantization-level VRAM fit.

Runs Q424GB VRAM availableRequires 4GB+

RTX 4090 meets the minimum VRAM requirement for Q4 inference of Microsoft Phi 3 Medium 128K Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for RTX 4090Best GPU guidesCompare prebuilt systems
Short answer: RTX 4090 can run Microsoft Phi 3 Medium 128K Instruct at Q4 with an estimated 180 tok/s.
Estimated speed
180 tok/s
VRAM needed
4GB
VRAM headroom
+20GB

What this means for you

RTX 4090 can run Microsoft Phi 3 Medium 128K Instruct with Q4 quantization. At approximately 180 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 20GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q44GB24GB180.00 tok/s✅ Fits comfortably
Q88GB24GB126.00 tok/s✅ Fits comfortably
FP1616GB24GB68.40 tok/s✅ Fits comfortably

Suitable alternatives

AMD Instinct MI300X
192GB
763.26 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Microsoft Phi 3 Medium 128K Instruct on AMD Instinct MI300X
NVIDIA H200 SXM 141GB
141GB
689.26 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Microsoft Phi 3 Medium 128K Instruct on NVIDIA H200 SXM 141GB
NVIDIA H100 SXM5 80GB
80GB
495.07 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Microsoft Phi 3 Medium 128K Instruct on NVIDIA H100 SXM5 80GB
AMD Instinct MI250X
128GB
477.56 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Microsoft Phi 3 Medium 128K Instruct on AMD Instinct MI250X
NVIDIA H100 PCIe 80GB
80GB
314.26 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Microsoft Phi 3 Medium 128K Instruct on NVIDIA H100 PCIe 80GB

Compare purchase paths

Direct GPU buy options

Check current pricing links for RTX 4090 and similar cards.

Open RTX 4090 buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

More questions

RTX 4090 buy options & pricingFull guide for Microsoft Phi 3 Medium 128K InstructBest GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksMicrosoft Phi 3 Medium 128K Instruct Q4 requirementsMicrosoft Phi 3 Medium 128K Instruct Q4_K_M requirementsCan AMD Instinct MI300X run Microsoft Phi 3 Medium 128K Instruct?Can NVIDIA H200 SXM 141GB run Microsoft Phi 3 Medium 128K Instruct?Can NVIDIA H100 SXM5 80GB run Microsoft Phi 3 Medium 128K Instruct?

Compatibility FAQ

Can RTX 4090 run Microsoft Phi 3 Medium 128K Instruct?

RTX 4090 can run Microsoft Phi 3 Medium 128K Instruct at Q4 with an estimated 180 tok/s.

How much VRAM is needed for Microsoft Phi 3 Medium 128K Instruct on RTX 4090?

Q4 inference is estimated to need about 4GB VRAM on this page, while RTX 4090 has 24GB available.

What if RTX 4090 is not enough for Microsoft Phi 3 Medium 128K Instruct?

If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.