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Can NVIDIA H100 SXM5 80GB run Openai Gpt Oss 20B?

Openai Gpt Oss 20B speed on NVIDIA H100 SXM5 80GB and quantization-level VRAM fit.

Runs Q480GB VRAM availableRequires 10GB+

NVIDIA H100 SXM5 80GB meets the minimum VRAM requirement for Q4 inference of Openai Gpt Oss 20B. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for NVIDIA H100 SXM5 80GBBest GPU guidesCompare prebuilt systems
Short answer: NVIDIA H100 SXM5 80GB can run Openai Gpt Oss 20B at Q4 with an estimated 272 tok/s.
Estimated speed
272 tok/s
VRAM needed
10GB
VRAM headroom
+70GB

What this means for you

NVIDIA H100 SXM5 80GB can run Openai Gpt Oss 20B with Q4 quantization. At approximately 272 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 70GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q410GB80GB272.29 tok/s✅ Fits comfortably
Q820GB80GB190.60 tok/s✅ Fits comfortably
FP1640GB80GB103.47 tok/s✅ Fits comfortably

Suitable alternatives

AMD Instinct MI300X
192GB
419.79 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Openai Gpt Oss 20B on AMD Instinct MI300X
NVIDIA H200 SXM 141GB
141GB
379.09 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Openai Gpt Oss 20B on NVIDIA H200 SXM 141GB
AMD Instinct MI250X
128GB
262.66 tok/s
Price: —
Fit note: compare VRAM and speed with your target workload before buying.
Check Openai Gpt Oss 20B on AMD Instinct MI250X
NVIDIA H100 PCIe 80GB
80GB
172.84 tok/s
Price: —
Fit note: compare VRAM and speed with your target workload before buying.
Check Openai Gpt Oss 20B on NVIDIA H100 PCIe 80GB
RTX 5090
32GB
164.87 tok/s
Price: —
Fit note: compare VRAM and speed with your target workload before buying.
Check Openai Gpt Oss 20B on RTX 5090

Compare purchase paths

Direct GPU buy options

Check current pricing links for NVIDIA H100 SXM5 80GB and similar cards.

Open NVIDIA H100 SXM5 80GB buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

Try before you buy

Rent cloud GPUs by the hour — no upfront hardware cost.

Vast.aiFrom $0.20/hr · Pay as you goRent GPU →RunPodFrom $0.30/hr · Secure cloudRent GPU →Lambda LabsFrom $0.50/hr · Enterprise-gradeRent GPU →

More questions

NVIDIA H100 SXM5 80GB buy options & pricingFull guide for Openai Gpt Oss 20BBest GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksOpenai Gpt Oss 20B Q4 requirementsOpenai Gpt Oss 20B Q4_K_M requirementsCan AMD Instinct MI300X run Openai Gpt Oss 20B?Can NVIDIA H200 SXM 141GB run Openai Gpt Oss 20B?Can AMD Instinct MI250X run Openai Gpt Oss 20B?openai gpt oss 20b speed on rtx 3080openai gpt oss 20b speed on rtx 5080

Compatibility FAQ

Can NVIDIA H100 SXM5 80GB run Openai Gpt Oss 20B?

NVIDIA H100 SXM5 80GB can run Openai Gpt Oss 20B at Q4 with an estimated 272 tok/s.

How much VRAM is needed for Openai Gpt Oss 20B on NVIDIA H100 SXM5 80GB?

Q4 inference is estimated to need about 10GB VRAM on this page, while NVIDIA H100 SXM5 80GB has 80GB available.

What if NVIDIA H100 SXM5 80GB is not enough for Openai Gpt Oss 20B?

If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.