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Can NVIDIA H100 SXM5 80GB run openai/gpt-oss-120b?

Runs Q480GB VRAM availableRequires 59GB+

NVIDIA H100 SXM5 80GB meets the minimum VRAM requirement for Q4 inference of openai/gpt-oss-120b. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

NVIDIA H100 SXM5 80GB can run openai/gpt-oss-120b with Q4 quantization. At approximately 105 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 21GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q459GB80GB105.45 tok/s✅ Fits comfortably
Q8117GB80GB72.82 tok/s❌ Not recommended
FP16235GB80GB34.98 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
144.31 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
124.97 tok/s
Price: —
AMD Instinct MI300X
192GB
112.06 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
103.75 tok/s
Price: —
AMD Instinct MI250X
128GB
97.11 tok/s
Price: —

More questions

NVIDIA H100 SXM5 80GB specs & pricingFull guide for openai/gpt-oss-120bopenai/gpt-oss-120b speed on NVIDIA H100 SXM5 80GBopenai/gpt-oss-120b Q4 requirements