NVIDIA H100 PCIe 80GB meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-Next-80B-A3B-Thinking. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
NVIDIA H100 PCIe 80GB can run Qwen/Qwen3-Next-80B-A3B-Thinking with Q4 quantization. At approximately 58 tokens/second, you can expect Good speed - acceptable for interactive use.
You have 41GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 39GB | 80GB | 57.67 tok/s | ✅ Fits comfortably |
| Q8 | 78GB | 80GB | 43.41 tok/s | ✅ Fits comfortably |
| FP16 | 156GB | 80GB | 25.99 tok/s | ❌ Not recommended |