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Can AMD Instinct MI300X run lmstudio-community/DeepSeek-R1-0528-Qwen3-8B-MLX-4bit?

Runs Q4192GB VRAM availableRequires 4GB+

AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of lmstudio-community/DeepSeek-R1-0528-Qwen3-8B-MLX-4bit. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI300X can run lmstudio-community/DeepSeek-R1-0528-Qwen3-8B-MLX-4bit with Q4 quantization. At approximately 791 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 188GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q44GB192GB790.66 tok/s✅ Fits comfortably
Q89GB192GB487.45 tok/s✅ Fits comfortably
FP1617GB192GB308.91 tok/s✅ Fits comfortably

Suitable alternatives

NVIDIA H200 SXM 141GB
141GB
654.44 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
529.27 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
498.96 tok/s
Price: —
AMD Instinct MI250X
128GB
498.93 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
363.35 tok/s
Price: —

More questions

AMD Instinct MI300X specs & pricingFull guide for lmstudio-community/DeepSeek-R1-0528-Qwen3-8B-MLX-4bitlmstudio-community/DeepSeek-R1-0528-Qwen3-8B-MLX-4bit speed on AMD Instinct MI300Xlmstudio-community/DeepSeek-R1-0528-Qwen3-8B-MLX-4bit Q4 requirements