AMD Instinct MI210 meets the minimum VRAM requirement for Q4 inference of openai/gpt-oss-safeguard-20b. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI210 can run openai/gpt-oss-safeguard-20b with Q4 quantization. At approximately 125 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 53GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 11GB | 64GB | 125.10 tok/s | ✅ Fits comfortably |
| Q8 | 22GB | 64GB | 95.32 tok/s | ✅ Fits comfortably |
| FP16 | 44GB | 64GB | 45.04 tok/s | ✅ Fits comfortably |