AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of openai/gpt-oss-safeguard-20b. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI300X can run openai/gpt-oss-safeguard-20b with Q4 quantization. At approximately 405 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 181GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 11GB | 192GB | 404.86 tok/s | ✅ Fits comfortably |
| Q8 | 22GB | 192GB | 283.49 tok/s | ✅ Fits comfortably |
| FP16 | 44GB | 192GB | 170.19 tok/s | ✅ Fits comfortably |