AMD Instinct MI210 meets the minimum VRAM requirement for Q4 inference of mlx-community/gpt-oss-20b-MXFP4-Q8. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI210 can run mlx-community/gpt-oss-20b-MXFP4-Q8 with Q4 quantization. At approximately 135 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 54GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 10GB | 64GB | 134.64 tok/s | ✅ Fits comfortably |
| Q8 | 20GB | 64GB | 92.41 tok/s | ✅ Fits comfortably |
| FP16 | 41GB | 64GB | 45.59 tok/s | ✅ Fits comfortably |