Mlx Community Gpt Oss 20B Mxfp4 Q8 speed on AMD Instinct MI300X and quantization-level VRAM fit.
AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of Mlx Community Gpt Oss 20B Mxfp4 Q8. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI300X can run Mlx Community Gpt Oss 20B Mxfp4 Q8 with Q4 quantization. At approximately 420 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 182GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 10GB | 192GB | 419.79 tok/s | ✅ Fits comfortably |
| Q8 | 20GB | 192GB | 293.85 tok/s | ✅ Fits comfortably |
| FP16 | 40GB | 192GB | 159.52 tok/s | ✅ Fits comfortably |
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AMD Instinct MI300X can run Mlx Community Gpt Oss 20B Mxfp4 Q8 at Q4 with an estimated 420 tok/s.
Q4 inference is estimated to need about 10GB VRAM on this page, while AMD Instinct MI300X has 192GB available.
If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.