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Can RTX 5080 run Qwen/Qwen2.5-7B-Instruct?

Runs Q416GB VRAM availableRequires 4GB+

RTX 5080 meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-7B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

RTX 5080 can run Qwen/Qwen2.5-7B-Instruct with Q4 quantization. At approximately 163 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 12GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q44GB16GB163.03 tok/s✅ Fits comfortably
Q87GB16GB107.89 tok/s✅ Fits comfortably
FP1615GB16GB65.50 tok/s⚠️ Tight fit

Suitable alternatives

AMD Instinct MI300X
192GB
715.55 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
628.37 tok/s
Price: —
AMD Instinct MI300X
192GB
551.61 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
517.25 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
477.49 tok/s
Price: —

More questions

RTX 5080 specs & pricingFull guide for Qwen/Qwen2.5-7B-InstructQwen/Qwen2.5-7B-Instruct speed on RTX 5080Qwen/Qwen2.5-7B-Instruct Q4 requirements