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Can RTX 5080 run Mistralai Mistral Large 3 675B Instruct 2512?

Mistralai Mistral Large 3 675B Instruct 2512 speed on RTX 5080 and quantization-level VRAM fit.

Q4 not recommended16GB VRAM availableRequires 338GB+

RTX 5080 does not meet the minimum VRAM requirement for Q4 inference of Mistralai Mistral Large 3 675B Instruct 2512. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for RTX 5080Best GPU guidesCompare prebuilt systems
Short answer: RTX 5080 is not a comfortable Q4 fit for Mistralai Mistral Large 3 675B Instruct 2512 (about 338GB needed).
Estimated speed
19 tok/s
VRAM needed
338GB
VRAM headroom
-322GB

What this means for you

RTX 5080 lacks sufficient VRAM for comfortable Mistralai Mistral Large 3 675B Instruct 2512 operation with Q4 quantization.

Your 16GB GPU is 322GB short of the 338GB minimum.

Options: (1) Try Q2 or Q3 quantization for lower VRAM requirements, (2) Consider cloud GPU rental, (3) Upgrade to a GPU with at least 16GB VRAM.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q4338GB16GB18.97 tok/s❌ Not recommended
Q8675GB16GB13.28 tok/s❌ Not recommended
FP161350GB16GB7.21 tok/s❌ Not recommended

Suitable alternatives

No alternative GPUs with verified compatibility yet. Expand the compatibility import to surface more cards.

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Direct GPU buy options

Check current pricing links for RTX 5080 and similar cards.

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Curated best GPU guides

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Prebuilt AI systems

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More questions

RTX 5080 buy options & pricingFull guide for Mistralai Mistral Large 3 675B Instruct 2512Best GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksMistralai Mistral Large 3 675B Instruct 2512 Q4 requirementsMistralai Mistral Large 3 675B Instruct 2512 Q4_K_M requirements

Compatibility FAQ

Can RTX 5080 run Mistralai Mistral Large 3 675B Instruct 2512?

RTX 5080 is not a comfortable Q4 fit for Mistralai Mistral Large 3 675B Instruct 2512 (about 338GB needed).

How much VRAM is needed for Mistralai Mistral Large 3 675B Instruct 2512 on RTX 5080?

Q4 inference is estimated to need about 338GB VRAM on this page, while RTX 5080 has 16GB available.

What if RTX 5080 is not enough for Mistralai Mistral Large 3 675B Instruct 2512?

Try lower-bit quantization, choose a smaller model, or move to a higher-VRAM GPU from the alternatives list.