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Can RTX 5080 run Meta Llama Llama 3.3 70B Instruct?

Meta Llama Llama 3.3 70B Instruct speed on RTX 5080 and quantization-level VRAM fit.

Q4 not recommended16GB VRAM availableRequires 35GB+

RTX 5080 does not meet the minimum VRAM requirement for Q4 inference of Meta Llama Llama 3.3 70B Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for RTX 5080Best GPU guidesCompare prebuilt systems
Short answer: RTX 5080 is not a comfortable Q4 fit for Meta Llama Llama 3.3 70B Instruct (about 35GB needed).
Estimated speed
55 tok/s
VRAM needed
35GB
VRAM headroom
-19GB

What this means for you

RTX 5080 lacks sufficient VRAM for comfortable Meta Llama Llama 3.3 70B Instruct operation with Q4 quantization.

Your 16GB GPU is 19GB short of the 35GB minimum.

Options: (1) Try Q2 or Q3 quantization for lower VRAM requirements, (2) Consider cloud GPU rental, (3) Upgrade to a GPU with at least 16GB VRAM.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q435GB16GB55.34 tok/s❌ Not recommended
Q870GB16GB38.74 tok/s❌ Not recommended
FP16140GB16GB21.03 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
267.14 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Meta Llama Llama 3.3 70B Instruct on AMD Instinct MI300X
NVIDIA H200 SXM 141GB
141GB
241.24 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Meta Llama Llama 3.3 70B Instruct on NVIDIA H200 SXM 141GB
NVIDIA H100 SXM5 80GB
80GB
173.27 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Meta Llama Llama 3.3 70B Instruct on NVIDIA H100 SXM5 80GB
AMD Instinct MI250X
128GB
167.14 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Meta Llama Llama 3.3 70B Instruct on AMD Instinct MI250X
NVIDIA H100 PCIe 80GB
80GB
109.99 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Meta Llama Llama 3.3 70B Instruct on NVIDIA H100 PCIe 80GB

Compare purchase paths

Direct GPU buy options

Check current pricing links for RTX 5080 and similar cards.

Open RTX 5080 buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

More questions

RTX 5080 buy options & pricingFull guide for Meta Llama Llama 3.3 70B InstructBest GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksMeta Llama Llama 3.3 70B Instruct Q4 requirementsMeta Llama Llama 3.3 70B Instruct Q4_K_M requirementsCan AMD Instinct MI300X run Meta Llama Llama 3.3 70B Instruct?Can NVIDIA H200 SXM 141GB run Meta Llama Llama 3.3 70B Instruct?Can NVIDIA H100 SXM5 80GB run Meta Llama Llama 3.3 70B Instruct?

Compatibility FAQ

Can RTX 5080 run Meta Llama Llama 3.3 70B Instruct?

RTX 5080 is not a comfortable Q4 fit for Meta Llama Llama 3.3 70B Instruct (about 35GB needed).

How much VRAM is needed for Meta Llama Llama 3.3 70B Instruct on RTX 5080?

Q4 inference is estimated to need about 35GB VRAM on this page, while RTX 5080 has 16GB available.

What if RTX 5080 is not enough for Meta Llama Llama 3.3 70B Instruct?

Try lower-bit quantization, choose a smaller model, or move to a higher-VRAM GPU from the alternatives list.