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Can RTX 4080 run OpenPipe/Qwen3-14B-Instruct?

Runs Q416GB VRAM availableRequires 7GB+

RTX 4080 meets the minimum VRAM requirement for Q4 inference of OpenPipe/Qwen3-14B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

RTX 4080 can run OpenPipe/Qwen3-14B-Instruct with Q4 quantization. At approximately 100 tokens/second, you can expect Good speed - acceptable for interactive use.

You have 9GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q47GB16GB99.61 tok/s✅ Fits comfortably
Q814GB16GB58.20 tok/s✅ Fits comfortably
FP1629GB16GB34.62 tok/s❌ Not recommended

Best current price

RTX 4080
$1,199.00 on Amazon
Check Price

Suitable alternatives

AMD Instinct MI300X
192GB
595.10 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
520.29 tok/s
Price: —
AMD Instinct MI300X
192GB
376.88 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
372.98 tok/s
Price: —
AMD Instinct MI250X
128GB
355.91 tok/s
Price: —

More questions

RTX 4080 specs & pricingFull guide for OpenPipe/Qwen3-14B-InstructOpenPipe/Qwen3-14B-Instruct speed on RTX 4080OpenPipe/Qwen3-14B-Instruct Q4 requirements