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Can RTX 4060 Ti 16GB run Mistralai Mistral Large Instruct 2411?

Mistralai Mistral Large Instruct 2411 speed on RTX 4060 Ti 16GB and quantization-level VRAM fit.

Q4 not recommended16GB VRAM availableRequires 62GB+

RTX 4060 Ti 16GB does not meet the minimum VRAM requirement for Q4 inference of Mistralai Mistral Large Instruct 2411. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for RTX 4060 Ti 16GBBest GPU guidesCompare prebuilt systems
Short answer: RTX 4060 Ti 16GB is not a comfortable Q4 fit for Mistralai Mistral Large Instruct 2411 (about 62GB needed).
Estimated speed
10 tok/s
VRAM needed
62GB
VRAM headroom
-46GB

What this means for you

RTX 4060 Ti 16GB lacks sufficient VRAM for comfortable Mistralai Mistral Large Instruct 2411 operation with Q4 quantization.

Your 16GB GPU is 46GB short of the 62GB minimum.

Options: (1) Try Q2 or Q3 quantization for lower VRAM requirements, (2) Consider cloud GPU rental, (3) Upgrade to a GPU with at least 16GB VRAM.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q462GB16GB10.10 tok/s❌ Not recommended
Q8123GB16GB7.07 tok/s❌ Not recommended
FP16246GB16GB3.84 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
152.65 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Mistralai Mistral Large Instruct 2411 on AMD Instinct MI300X
NVIDIA H200 SXM 141GB
141GB
137.85 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Mistralai Mistral Large Instruct 2411 on NVIDIA H200 SXM 141GB
NVIDIA H100 SXM5 80GB
80GB
99.01 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Mistralai Mistral Large Instruct 2411 on NVIDIA H100 SXM5 80GB
AMD Instinct MI250X
128GB
95.51 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Mistralai Mistral Large Instruct 2411 on AMD Instinct MI250X
NVIDIA H100 PCIe 80GB
80GB
62.85 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Mistralai Mistral Large Instruct 2411 on NVIDIA H100 PCIe 80GB
Need more VRAM for Mistralai Mistral Large Instruct 2411?
RTX 4060 Ti 16GB is 46GB short. Consider a GPU with 81GB+ VRAM.
Best GPU for 70B Models →Best GPU for Deep Learning →All buying guides →

Compare purchase paths

Direct GPU buy options

Check current pricing links for RTX 4060 Ti 16GB and similar cards.

Open RTX 4060 Ti 16GB buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

Not ready to upgrade?

Your GPU doesn't meet the VRAM requirements. Run Mistralai Mistral Large Instruct 2411 on cloud GPU instantly.

Vast.aiFrom $0.20/hr · Pay as you goRent GPU →RunPodFrom $0.30/hr · Secure cloudRent GPU →Lambda LabsFrom $0.50/hr · Enterprise-gradeRent GPU →

More questions

RTX 4060 Ti 16GB buy options & pricingFull guide for Mistralai Mistral Large Instruct 2411Best GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksMistralai Mistral Large Instruct 2411 Q4 requirementsMistralai Mistral Large Instruct 2411 Q4_K_M requirementsCan AMD Instinct MI300X run Mistralai Mistral Large Instruct 2411?Can NVIDIA H200 SXM 141GB run Mistralai Mistral Large Instruct 2411?Can NVIDIA H100 SXM5 80GB run Mistralai Mistral Large Instruct 2411?

Compatibility FAQ

Can RTX 4060 Ti 16GB run Mistralai Mistral Large Instruct 2411?

RTX 4060 Ti 16GB is not a comfortable Q4 fit for Mistralai Mistral Large Instruct 2411 (about 62GB needed).

How much VRAM is needed for Mistralai Mistral Large Instruct 2411 on RTX 4060 Ti 16GB?

Q4 inference is estimated to need about 62GB VRAM on this page, while RTX 4060 Ti 16GB has 16GB available.

What if RTX 4060 Ti 16GB is not enough for Mistralai Mistral Large Instruct 2411?

Try lower-bit quantization, choose a smaller model, or move to a higher-VRAM GPU from the alternatives list.