NVIDIA L40S meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-72B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
NVIDIA L40S can run Qwen/Qwen2.5-72B-Instruct with Q4 quantization. At approximately 31 tokens/second, you can expect Moderate speed - useful for batch processing.
You have 12GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 36GB | 48GB | 31.20 tok/s | ✅ Fits comfortably |
| Q8 | 71GB | 48GB | 23.22 tok/s | ❌ Not recommended |
| FP16 | 142GB | 48GB | 13.62 tok/s | ❌ Not recommended |