NVIDIA H100 PCIe 80GB meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-4B-Instruct-2507. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
NVIDIA H100 PCIe 80GB can run Qwen/Qwen3-4B-Instruct-2507 with Q4 quantization. At approximately 335 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 78GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 2GB | 80GB | 334.93 tok/s | ✅ Fits comfortably |
| Q8 | 4GB | 80GB | 224.78 tok/s | ✅ Fits comfortably |
| FP16 | 9GB | 80GB | 121.34 tok/s | ✅ Fits comfortably |