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Can AMD Ryzen AI Max 385 run Qwen/Qwen2.5-0.5B-Instruct?

Runs Q4128GB VRAM availableRequires 3GB+

AMD Ryzen AI Max 385 meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-0.5B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Ryzen AI Max 385 can run Qwen/Qwen2.5-0.5B-Instruct with Q4 quantization. At approximately 34 tokens/second, you can expect Moderate speed - useful for batch processing.

You have 125GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q43GB128GB34.10 tok/s✅ Fits comfortably
Q85GB128GB25.96 tok/s✅ Fits comfortably
FP1611GB128GB14.82 tok/s✅ Fits comfortably

Suitable alternatives

AMD Instinct MI300X
192GB
826.46 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
622.64 tok/s
Price: —
AMD Instinct MI300X
192GB
539.44 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
479.18 tok/s
Price: —
AMD Instinct MI250X
128GB
475.49 tok/s
Price: —

More questions

AMD Ryzen AI Max 385 specs & pricingFull guide for Qwen/Qwen2.5-0.5B-InstructQwen/Qwen2.5-0.5B-Instruct speed on AMD Ryzen AI Max 385Qwen/Qwen2.5-0.5B-Instruct Q4 requirements