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Can AMD Ryzen AI Max 385 run Mistralai Mistral Large 3 675B Instruct 2512?

Mistralai Mistral Large 3 675B Instruct 2512 speed on AMD Ryzen AI Max 385 and quantization-level VRAM fit.

Q4 not recommended128GB VRAM availableRequires 338GB+

AMD Ryzen AI Max 385 does not meet the minimum VRAM requirement for Q4 inference of Mistralai Mistral Large 3 675B Instruct 2512. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for AMD Ryzen AI Max 385Best GPU guidesCompare prebuilt systems
Short answer: AMD Ryzen AI Max 385 is not a comfortable Q4 fit for Mistralai Mistral Large 3 675B Instruct 2512 (about 338GB needed).
Estimated speed
4 tok/s
VRAM needed
338GB
VRAM headroom
-210GB

What this means for you

AMD Ryzen AI Max 385 lacks sufficient VRAM for comfortable Mistralai Mistral Large 3 675B Instruct 2512 operation with Q4 quantization.

Your 128GB GPU is 210GB short of the 338GB minimum.

Options: (1) Try Q2 or Q3 quantization for lower VRAM requirements, (2) Consider cloud GPU rental, (3) Upgrade to a GPU with at least 16GB VRAM.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q4338GB128GB4.38 tok/s❌ Not recommended
Q8675GB128GB3.07 tok/s❌ Not recommended
FP161350GB128GB1.66 tok/s❌ Not recommended

Suitable alternatives

No alternative GPUs with verified compatibility yet. Expand the compatibility import to surface more cards.

Need more VRAM for Mistralai Mistral Large 3 675B Instruct 2512?
AMD Ryzen AI Max 385 is 210GB short. Consider a GPU with 440GB+ VRAM.
Best GPU for 70B Models →Best GPU for Deep Learning →All buying guides →

Compare purchase paths

Direct GPU buy options

Check current pricing links for AMD Ryzen AI Max 385 and similar cards.

Open AMD Ryzen AI Max 385 buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

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Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

Not ready to upgrade?

Your GPU doesn't meet the VRAM requirements. Run Mistralai Mistral Large 3 675B Instruct 2512 on cloud GPU instantly.

Vast.aiFrom $0.20/hr · Pay as you goRent GPU →RunPodFrom $0.30/hr · Secure cloudRent GPU →Lambda LabsFrom $0.50/hr · Enterprise-gradeRent GPU →

More questions

AMD Ryzen AI Max 385 buy options & pricingFull guide for Mistralai Mistral Large 3 675B Instruct 2512Best GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksMistralai Mistral Large 3 675B Instruct 2512 Q4 requirementsMistralai Mistral Large 3 675B Instruct 2512 Q4_K_M requirements

Compatibility FAQ

Can AMD Ryzen AI Max 385 run Mistralai Mistral Large 3 675B Instruct 2512?

AMD Ryzen AI Max 385 is not a comfortable Q4 fit for Mistralai Mistral Large 3 675B Instruct 2512 (about 338GB needed).

How much VRAM is needed for Mistralai Mistral Large 3 675B Instruct 2512 on AMD Ryzen AI Max 385?

Q4 inference is estimated to need about 338GB VRAM on this page, while AMD Ryzen AI Max 385 has 128GB available.

What if AMD Ryzen AI Max 385 is not enough for Mistralai Mistral Large 3 675B Instruct 2512?

Try lower-bit quantization, choose a smaller model, or move to a higher-VRAM GPU from the alternatives list.