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Can AMD Radeon Pro W7800 run Qwen Qwen2 5 72B Instruct?

Qwen Qwen2 5 72B Instruct speed on AMD Radeon Pro W7800 and quantization-level VRAM fit.

Q4 not recommended32GB VRAM availableRequires 37GB+

AMD Radeon Pro W7800 does not meet the minimum VRAM requirement for Q4 inference of Qwen Qwen2 5 72B Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for AMD Radeon Pro W7800Best GPU guidesCompare prebuilt systems
Short answer: AMD Radeon Pro W7800 is not a comfortable Q4 fit for Qwen Qwen2 5 72B Instruct (about 37GB needed).
Estimated speed
18 tok/s
VRAM needed
37GB
VRAM headroom
-5GB

What this means for you

AMD Radeon Pro W7800 lacks sufficient VRAM for comfortable Qwen Qwen2 5 72B Instruct operation with Q4 quantization.

Your 32GB GPU is 5GB short of the 37GB minimum.

Options: (1) Try Q2 or Q3 quantization for lower VRAM requirements, (2) Consider cloud GPU rental, (3) Upgrade to a GPU with at least 16GB VRAM.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q437GB32GB17.89 tok/s❌ Not recommended
Q873GB32GB12.52 tok/s❌ Not recommended
FP16146GB32GB6.80 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
152.65 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Qwen Qwen2 5 72B Instruct on AMD Instinct MI300X
NVIDIA H200 SXM 141GB
141GB
137.85 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Qwen Qwen2 5 72B Instruct on NVIDIA H200 SXM 141GB
NVIDIA H100 SXM5 80GB
80GB
99.01 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Qwen Qwen2 5 72B Instruct on NVIDIA H100 SXM5 80GB
AMD Instinct MI250X
128GB
95.51 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Qwen Qwen2 5 72B Instruct on AMD Instinct MI250X
NVIDIA H100 PCIe 80GB
80GB
62.85 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Qwen Qwen2 5 72B Instruct on NVIDIA H100 PCIe 80GB
Need more VRAM for Qwen Qwen2 5 72B Instruct?
AMD Radeon Pro W7800 is 5GB short. Consider a GPU with 49GB+ VRAM.
Best GPU for 70B Models →Best GPU for Deep Learning →All buying guides →

Compare purchase paths

Direct GPU buy options

Check current pricing links for AMD Radeon Pro W7800 and similar cards.

Open AMD Radeon Pro W7800 buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

Not ready to upgrade?

Your GPU doesn't meet the VRAM requirements. Run Qwen Qwen2 5 72B Instruct on cloud GPU instantly.

Vast.aiFrom $0.20/hr · Pay as you goRent GPU →RunPodFrom $0.30/hr · Secure cloudRent GPU →Lambda LabsFrom $0.50/hr · Enterprise-gradeRent GPU →

More questions

AMD Radeon Pro W7800 buy options & pricingFull guide for Qwen Qwen2 5 72B InstructBest GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksQwen Qwen2 5 72B Instruct Q4 requirementsQwen Qwen2 5 72B Instruct Q4_K_M requirementsCan AMD Instinct MI300X run Qwen Qwen2 5 72B Instruct?Can NVIDIA H200 SXM 141GB run Qwen Qwen2 5 72B Instruct?Can NVIDIA H100 SXM5 80GB run Qwen Qwen2 5 72B Instruct?

Compatibility FAQ

Can AMD Radeon Pro W7800 run Qwen Qwen2 5 72B Instruct?

AMD Radeon Pro W7800 is not a comfortable Q4 fit for Qwen Qwen2 5 72B Instruct (about 37GB needed).

How much VRAM is needed for Qwen Qwen2 5 72B Instruct on AMD Radeon Pro W7800?

Q4 inference is estimated to need about 37GB VRAM on this page, while AMD Radeon Pro W7800 has 32GB available.

What if AMD Radeon Pro W7800 is not enough for Qwen Qwen2 5 72B Instruct?

Try lower-bit quantization, choose a smaller model, or move to a higher-VRAM GPU from the alternatives list.