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Can AMD Instinct MI300X run Qwen/Qwen3-4B-Thinking-2507-FP8?

Runs Q4192GB VRAM availableRequires 2GB+

AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-4B-Thinking-2507-FP8. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI300X can run Qwen/Qwen3-4B-Thinking-2507-FP8 with Q4 quantization. At approximately 777 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 190GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q42GB192GB776.99 tok/s✅ Fits comfortably
Q84GB192GB483.42 tok/s✅ Fits comfortably
FP169GB192GB264.26 tok/s✅ Fits comfortably

Suitable alternatives

NVIDIA H200 SXM 141GB
141GB
736.14 tok/s
Price: —
AMD Instinct MI250X
128GB
490.58 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
467.70 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
435.90 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
378.75 tok/s
Price: —

More questions

AMD Instinct MI300X specs & pricingFull guide for Qwen/Qwen3-4B-Thinking-2507-FP8Qwen/Qwen3-4B-Thinking-2507-FP8 speed on AMD Instinct MI300XQwen/Qwen3-4B-Thinking-2507-FP8 Q4 requirements