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Can AMD Instinct MI300X run Qwen/Qwen3-14B?

Runs Q4192GB VRAM availableRequires 7GB+

AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-14B. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI300X can run Qwen/Qwen3-14B with Q4 quantization. At approximately 525 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 185GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q47GB192GB525.10 tok/s✅ Fits comfortably
Q814GB192GB420.17 tok/s✅ Fits comfortably
FP1629GB192GB225.81 tok/s✅ Fits comfortably

Suitable alternatives

NVIDIA H200 SXM 141GB
141GB
556.39 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
389.98 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
383.02 tok/s
Price: —
AMD Instinct MI250X
128GB
382.26 tok/s
Price: —
AMD Instinct MI250X
128GB
256.65 tok/s
Price: —

More questions

AMD Instinct MI300X specs & pricingFull guide for Qwen/Qwen3-14BQwen/Qwen3-14B speed on AMD Instinct MI300XQwen/Qwen3-14B Q4 requirements