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Can AMD Instinct MI300X run Qwen/Qwen2.5-14B-Instruct?

Runs Q4192GB VRAM availableRequires 8GB+

AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-14B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI300X can run Qwen/Qwen2.5-14B-Instruct with Q4 quantization. At approximately 550 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 184GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q48GB192GB549.54 tok/s✅ Fits comfortably
Q815GB192GB439.84 tok/s✅ Fits comfortably
FP1630GB192GB237.62 tok/s✅ Fits comfortably

Suitable alternatives

NVIDIA H200 SXM 141GB
141GB
539.79 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
374.83 tok/s
Price: —
AMD Instinct MI250X
128GB
367.79 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
338.35 tok/s
Price: —
AMD Instinct MI250X
128GB
270.55 tok/s
Price: —

More questions

AMD Instinct MI300X specs & pricingFull guide for Qwen/Qwen2.5-14B-InstructQwen/Qwen2.5-14B-Instruct speed on AMD Instinct MI300XQwen/Qwen2.5-14B-Instruct Q4 requirements