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Can AMD Instinct MI300X run microsoft/phi-4?

Runs Q4192GB VRAM availableRequires 4GB+

AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of microsoft/phi-4. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI300X can run microsoft/phi-4 with Q4 quantization. At approximately 782 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 188GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q44GB192GB782.00 tok/s✅ Fits comfortably
Q87GB192GB484.71 tok/s✅ Fits comfortably
FP1615GB192GB266.51 tok/s✅ Fits comfortably

Suitable alternatives

NVIDIA H200 SXM 141GB
141GB
756.72 tok/s
Price: —
AMD Instinct MI250X
128GB
520.91 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
501.19 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
487.86 tok/s
Price: —
RTX 5090
32GB
327.31 tok/s
Price: —

More questions

AMD Instinct MI300X specs & pricingFull guide for microsoft/phi-4microsoft/phi-4 speed on AMD Instinct MI300Xmicrosoft/phi-4 Q4 requirements