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Can AMD Instinct MI300X run lmstudio-community/Qwen3-4B-Thinking-2507-MLX-4bit?

Runs Q4192GB VRAM availableRequires 2GB+

AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of lmstudio-community/Qwen3-4B-Thinking-2507-MLX-4bit. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI300X can run lmstudio-community/Qwen3-4B-Thinking-2507-MLX-4bit with Q4 quantization. At approximately 704 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 190GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q42GB192GB703.79 tok/s✅ Fits comfortably
Q84GB192GB506.76 tok/s✅ Fits comfortably
FP169GB192GB292.31 tok/s✅ Fits comfortably

Suitable alternatives

NVIDIA H200 SXM 141GB
141GB
717.88 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
527.65 tok/s
Price: —
AMD Instinct MI250X
128GB
485.77 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
449.07 tok/s
Price: —
AMD Instinct MI250X
128GB
350.76 tok/s
Price: —

More questions

AMD Instinct MI300X specs & pricingFull guide for lmstudio-community/Qwen3-4B-Thinking-2507-MLX-4bitlmstudio-community/Qwen3-4B-Thinking-2507-MLX-4bit speed on AMD Instinct MI300Xlmstudio-community/Qwen3-4B-Thinking-2507-MLX-4bit Q4 requirements