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Can AMD Instinct MI300X run Deepseek AI Deepseek Coder 33B Instruct?

Deepseek AI Deepseek Coder 33B Instruct speed on AMD Instinct MI300X and quantization-level VRAM fit.

Runs Q4192GB VRAM availableRequires 17GB+

AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of Deepseek AI Deepseek Coder 33B Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for AMD Instinct MI300XBest GPU guidesCompare prebuilt systems
Short answer: AMD Instinct MI300X can run Deepseek AI Deepseek Coder 33B Instruct at Q4 with an estimated 334 tok/s.
Estimated speed
334 tok/s
VRAM needed
17GB
VRAM headroom
+175GB

What this means for you

AMD Instinct MI300X can run Deepseek AI Deepseek Coder 33B Instruct with Q4 quantization. At approximately 334 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 175GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q417GB192GB333.93 tok/s✅ Fits comfortably
Q833GB192GB233.75 tok/s✅ Fits comfortably
FP1666GB192GB126.89 tok/s✅ Fits comfortably

Suitable alternatives

NVIDIA H200 SXM 141GB
141GB
301.55 tok/s
Price: —
Fit note: compare VRAM and speed with your target workload before buying.
Check Deepseek AI Deepseek Coder 33B Instruct on NVIDIA H200 SXM 141GB
NVIDIA H100 SXM5 80GB
80GB
216.59 tok/s
Price: —
Fit note: compare VRAM and speed with your target workload before buying.
Check Deepseek AI Deepseek Coder 33B Instruct on NVIDIA H100 SXM5 80GB
AMD Instinct MI250X
128GB
208.93 tok/s
Price: —
Fit note: compare VRAM and speed with your target workload before buying.
Check Deepseek AI Deepseek Coder 33B Instruct on AMD Instinct MI250X
NVIDIA H100 PCIe 80GB
80GB
137.49 tok/s
Price: —
Fit note: compare VRAM and speed with your target workload before buying.
Check Deepseek AI Deepseek Coder 33B Instruct on NVIDIA H100 PCIe 80GB
RTX 5090
32GB
131.15 tok/s
Price: —
Fit note: compare VRAM and speed with your target workload before buying.
Check Deepseek AI Deepseek Coder 33B Instruct on RTX 5090

GPU buying guides

Need a GPU with 17GB+ VRAM? These guides match your requirements.

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Compare purchase paths

Direct GPU buy options

Check current pricing links for AMD Instinct MI300X and similar cards.

Open AMD Instinct MI300X buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

Try before you buy

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More questions

AMD Instinct MI300X buy options & pricingFull guide for Deepseek AI Deepseek Coder 33B InstructBest GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksDeepseek AI Deepseek Coder 33B Instruct Q4 requirementsDeepseek AI Deepseek Coder 33B Instruct Q4_K_M requirementsCan NVIDIA H200 SXM 141GB run Deepseek AI Deepseek Coder 33B Instruct?Can NVIDIA H100 SXM5 80GB run Deepseek AI Deepseek Coder 33B Instruct?Can AMD Instinct MI250X run Deepseek AI Deepseek Coder 33B Instruct?deepseek ai deepseek coder 33b instruct speed on apple m3 max

Compatibility FAQ

Can AMD Instinct MI300X run Deepseek AI Deepseek Coder 33B Instruct?

AMD Instinct MI300X can run Deepseek AI Deepseek Coder 33B Instruct at Q4 with an estimated 334 tok/s.

How much VRAM is needed for Deepseek AI Deepseek Coder 33B Instruct on AMD Instinct MI300X?

Q4 inference is estimated to need about 17GB VRAM on this page, while AMD Instinct MI300X has 192GB available.

What if AMD Instinct MI300X is not enough for Deepseek AI Deepseek Coder 33B Instruct?

If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.