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Can AMD Instinct MI250X run Qwen/Qwen3-Coder-Next?

Runs Q4128GB VRAM availableRequires 45GB+

AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-Coder-Next. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI250X can run Qwen/Qwen3-Coder-Next with Q4 quantization. At approximately 97 tokens/second, you can expect Good speed - acceptable for interactive use.

You have 83GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q445GB128GB96.52 tok/s✅ Fits comfortably
Q890GB128GB67.30 tok/s✅ Fits comfortably
FP16179GB128GB33.28 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
140.03 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
124.22 tok/s
Price: —
AMD Instinct MI300X
192GB
117.30 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
103.46 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
94.62 tok/s
Price: —

More questions

AMD Instinct MI250X specs & pricingFull guide for Qwen/Qwen3-Coder-NextQwen/Qwen3-Coder-Next speed on AMD Instinct MI250XQwen/Qwen3-Coder-Next Q4 requirements