AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-8B-FP8. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI250X can run Qwen/Qwen3-8B-FP8 with Q4 quantization. At approximately 513 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 124GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 4GB | 128GB | 513.39 tok/s | ✅ Fits comfortably |
| Q8 | 9GB | 128GB | 343.16 tok/s | ✅ Fits comfortably |
| FP16 | 17GB | 128GB | 199.16 tok/s | ✅ Fits comfortably |