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GPUs for AI Models: Benchmarks & Specs

Can AMD Instinct MI250X run Qwen/Qwen3-235B-A22B?

Runs Q4128GB VRAM availableRequires 115GB+

AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-235B-A22B. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Quantization breakdown

Quantization	VRAM needed	VRAM available	Estimated speed	Verdict
Q4	115GB	128GB	55.37 tok/s	✅ Fits comfortably
Q8	230GB	128GB	40.63 tok/s	❌ Not recommended
FP16	460GB	128GB	19.81 tok/s	❌ Not recommended

Suitable alternatives

NVIDIA H200 SXM 141GB

141GB

87.23 tok/s

Price: —

AMD Instinct MI300X

192GB

82.52 tok/s

Price: —

192GB

More questions

AMD Instinct MI250X specs & pricing Full guide for Qwen/Qwen3-235B-A22B