AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-14B. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI250X can run Qwen/Qwen3-14B with Q4 quantization. At approximately 382 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 121GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 7GB | 128GB | 382.26 tok/s | ✅ Fits comfortably |
| Q8 | 14GB | 128GB | 256.65 tok/s | ✅ Fits comfortably |
| FP16 | 29GB | 128GB | 130.81 tok/s | ✅ Fits comfortably |