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Can AMD Instinct MI250X run Qwen/Qwen3-0.6B?

Runs Q4128GB VRAM availableRequires 3GB+

AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-0.6B. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI250X can run Qwen/Qwen3-0.6B with Q4 quantization. At approximately 476 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 125GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q43GB128GB476.00 tok/s✅ Fits comfortably
Q86GB128GB341.41 tok/s✅ Fits comfortably
FP1613GB128GB194.29 tok/s✅ Fits comfortably

Suitable alternatives

AMD Instinct MI300X
192GB
755.55 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
712.18 tok/s
Price: —
AMD Instinct MI300X
192GB
527.18 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
498.41 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
498.18 tok/s
Price: —

More questions

AMD Instinct MI250X specs & pricingFull guide for Qwen/Qwen3-0.6BQwen/Qwen3-0.6B speed on AMD Instinct MI250XQwen/Qwen3-0.6B Q4 requirements