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GPUs for AI Models: Benchmarks & Specs

Can AMD Instinct MI250X run mistralai/Ministral-3-14B-Instruct-2512?

Runs Q4128GB VRAM availableRequires 8GB+

AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of mistralai/Ministral-3-14B-Instruct-2512. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Quantization breakdown

Quantization	VRAM needed	VRAM available	Estimated speed	Verdict
Q4	8GB	128GB	363.71 tok/s	✅ Fits comfortably
Q8	16GB	128GB	246.54 tok/s	✅ Fits comfortably
FP16	32GB	128GB	125.25 tok/s	✅ Fits comfortably

Suitable alternatives

AMD Instinct MI300X

192GB

599.22 tok/s

Price: —

NVIDIA H200 SXM 141GB

141GB

498.23 tok/s

Price: —

AMD Instinct MI300X

192GB

More questions

AMD Instinct MI250X specs & pricing Full guide for mistralai/Ministral-3-14B-Instruct-2512