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Can AMD Instinct MI250X run Gensyn/Qwen2.5-0.5B-Instruct?

Runs Q4128GB VRAM availableRequires 3GB+

AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of Gensyn/Qwen2.5-0.5B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI250X can run Gensyn/Qwen2.5-0.5B-Instruct with Q4 quantization. At approximately 510 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 125GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q43GB128GB509.95 tok/s✅ Fits comfortably
Q85GB128GB334.88 tok/s✅ Fits comfortably
FP1611GB128GB181.05 tok/s✅ Fits comfortably

Suitable alternatives

AMD Instinct MI300X
192GB
715.86 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
681.20 tok/s
Price: —
AMD Instinct MI300X
192GB
557.51 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
501.15 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
466.47 tok/s
Price: —

More questions

AMD Instinct MI250X specs & pricingFull guide for Gensyn/Qwen2.5-0.5B-InstructGensyn/Qwen2.5-0.5B-Instruct speed on AMD Instinct MI250XGensyn/Qwen2.5-0.5B-Instruct Q4 requirements