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Can AMD Instinct MI250X run AI Mo Kimina Prover 72B?

AI Mo Kimina Prover 72B speed on AMD Instinct MI250X and quantization-level VRAM fit.

Runs Q4128GB VRAM availableRequires 36GB+

AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of AI Mo Kimina Prover 72B. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for AMD Instinct MI250XBest GPU guidesCompare prebuilt systems
Short answer: AMD Instinct MI250X can run AI Mo Kimina Prover 72B at Q4 with an estimated 96 tok/s.
Estimated speed
96 tok/s
VRAM needed
36GB
VRAM headroom
+92GB

What this means for you

AMD Instinct MI250X can run AI Mo Kimina Prover 72B with Q4 quantization. At approximately 96 tokens/second, you can expect Good speed - acceptable for interactive use.

You have 92GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q436GB128GB95.51 tok/s✅ Fits comfortably
Q872GB128GB66.86 tok/s✅ Fits comfortably
FP16144GB128GB36.29 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
152.65 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check AI Mo Kimina Prover 72B on AMD Instinct MI300X
NVIDIA H200 SXM 141GB
141GB
137.85 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check AI Mo Kimina Prover 72B on NVIDIA H200 SXM 141GB
NVIDIA H100 SXM5 80GB
80GB
99.01 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check AI Mo Kimina Prover 72B on NVIDIA H100 SXM5 80GB
NVIDIA H100 PCIe 80GB
80GB
62.85 tok/s
Price: —
Fit note: compare VRAM and speed with your target workload before buying.
Check AI Mo Kimina Prover 72B on NVIDIA H100 PCIe 80GB
NVIDIA A100 80GB SXM4
80GB
58.41 tok/s
Price: —
Fit note: compare VRAM and speed with your target workload before buying.
Check AI Mo Kimina Prover 72B on NVIDIA A100 80GB SXM4

GPU buying guides

Need a GPU with 36GB+ VRAM? These guides match your requirements.

Best GPU for 70B Models
Hardware for running 70B-class models with realistic tradeoffs.
Read guide →
Best GPU for LLMs
Optimized for running large language models locally.
Read guide →

Compare purchase paths

Direct GPU buy options

Check current pricing links for AMD Instinct MI250X and similar cards.

Open AMD Instinct MI250X buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

Try before you buy

Rent cloud GPUs by the hour — no upfront hardware cost.

Vast.aiFrom $0.20/hr · Pay as you goRent GPU →RunPodFrom $0.30/hr · Secure cloudRent GPU →Lambda LabsFrom $0.50/hr · Enterprise-gradeRent GPU →

More questions

AMD Instinct MI250X buy options & pricingFull guide for AI Mo Kimina Prover 72BBest GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksAI Mo Kimina Prover 72B Q4 requirementsAI Mo Kimina Prover 72B Q4_K_M requirementsCan AMD Instinct MI300X run AI Mo Kimina Prover 72B?Can NVIDIA H200 SXM 141GB run AI Mo Kimina Prover 72B?Can NVIDIA H100 SXM5 80GB run AI Mo Kimina Prover 72B?

Compatibility FAQ

Can AMD Instinct MI250X run AI Mo Kimina Prover 72B?

AMD Instinct MI250X can run AI Mo Kimina Prover 72B at Q4 with an estimated 96 tok/s.

How much VRAM is needed for AI Mo Kimina Prover 72B on AMD Instinct MI250X?

Q4 inference is estimated to need about 36GB VRAM on this page, while AMD Instinct MI250X has 128GB available.

What if AMD Instinct MI250X is not enough for AI Mo Kimina Prover 72B?

If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.