AMD Instinct MI210 meets the minimum VRAM requirement for Q4 inference of unsloth/gpt-oss-20b-BF16. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI210 can run unsloth/gpt-oss-20b-BF16 with Q4 quantization. At approximately 129 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 54GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 10GB | 64GB | 129.46 tok/s | ✅ Fits comfortably |
| Q8 | 20GB | 64GB | 88.28 tok/s | ✅ Fits comfortably |
| FP16 | 41GB | 64GB | 49.15 tok/s | ✅ Fits comfortably |