Qwen Qwen3 Next 80B A3b Instruct speed on AMD Instinct MI210 and quantization-level VRAM fit.
AMD Instinct MI210 meets the minimum VRAM requirement for Q4 inference of Qwen Qwen3 Next 80B A3b Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI210 can run Qwen Qwen3 Next 80B A3b Instruct with Q4 quantization. At approximately 48 tokens/second, you can expect Moderate speed - useful for batch processing.
You have 24GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 40GB | 64GB | 47.53 tok/s | ✅ Fits comfortably |
| Q8 | 80GB | 64GB | 33.27 tok/s | ❌ Not recommended |
| FP16 | 160GB | 64GB | 18.06 tok/s | ❌ Not recommended |
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AMD Instinct MI210 can run Qwen Qwen3 Next 80B A3b Instruct at Q4 with an estimated 48 tok/s.
Q4 inference is estimated to need about 40GB VRAM on this page, while AMD Instinct MI210 has 64GB available.
If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.