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Can AMD Instinct MI210 run NVIDIA Llama 3 1 Nemotron 70B Instruct HF?

NVIDIA Llama 3 1 Nemotron 70B Instruct HF speed on AMD Instinct MI210 and quantization-level VRAM fit.

Runs Q464GB VRAM availableRequires 35GB+

AMD Instinct MI210 meets the minimum VRAM requirement for Q4 inference of NVIDIA Llama 3 1 Nemotron 70B Instruct HF. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for AMD Instinct MI210Best GPU guidesCompare prebuilt systems
Short answer: AMD Instinct MI210 can run NVIDIA Llama 3 1 Nemotron 70B Instruct HF at Q4 with an estimated 83 tok/s.
Estimated speed
83 tok/s
VRAM needed
35GB
VRAM headroom
+29GB

What this means for you

AMD Instinct MI210 can run NVIDIA Llama 3 1 Nemotron 70B Instruct HF with Q4 quantization. At approximately 83 tokens/second, you can expect Good speed - acceptable for interactive use.

You have 29GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q435GB64GB83.18 tok/s✅ Fits comfortably
Q870GB64GB58.23 tok/s❌ Not recommended
FP16140GB64GB31.61 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
267.14 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check NVIDIA Llama 3 1 Nemotron 70B Instruct HF on AMD Instinct MI300X
NVIDIA H200 SXM 141GB
141GB
241.24 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check NVIDIA Llama 3 1 Nemotron 70B Instruct HF on NVIDIA H200 SXM 141GB
NVIDIA H100 SXM5 80GB
80GB
173.27 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check NVIDIA Llama 3 1 Nemotron 70B Instruct HF on NVIDIA H100 SXM5 80GB
AMD Instinct MI250X
128GB
167.14 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check NVIDIA Llama 3 1 Nemotron 70B Instruct HF on AMD Instinct MI250X
NVIDIA H100 PCIe 80GB
80GB
109.99 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check NVIDIA Llama 3 1 Nemotron 70B Instruct HF on NVIDIA H100 PCIe 80GB

GPU buying guides

Need a GPU with 35GB+ VRAM? These guides match your requirements.

Best GPU for Llama 3
GPU picks tuned for Llama 3 inference from 8B to 70B.
Read guide →
Best GPU for 70B Models
Hardware for running 70B-class models with realistic tradeoffs.
Read guide →
Best GPU for LLMs
Optimized for running large language models locally.
Read guide →

Compare purchase paths

Direct GPU buy options

Check current pricing links for AMD Instinct MI210 and similar cards.

Open AMD Instinct MI210 buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

Try before you buy

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Vast.aiFrom $0.20/hr · Pay as you goRent GPU →RunPodFrom $0.30/hr · Secure cloudRent GPU →Lambda LabsFrom $0.50/hr · Enterprise-gradeRent GPU →

More questions

AMD Instinct MI210 buy options & pricingFull guide for NVIDIA Llama 3 1 Nemotron 70B Instruct HFBest GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksNVIDIA Llama 3 1 Nemotron 70B Instruct HF Q4 requirementsNVIDIA Llama 3 1 Nemotron 70B Instruct HF Q4_K_M requirementsCan AMD Instinct MI300X run NVIDIA Llama 3 1 Nemotron 70B Instruct HF?Can NVIDIA H200 SXM 141GB run NVIDIA Llama 3 1 Nemotron 70B Instruct HF?Can NVIDIA H100 SXM5 80GB run NVIDIA Llama 3 1 Nemotron 70B Instruct HF?

Compatibility FAQ

Can AMD Instinct MI210 run NVIDIA Llama 3 1 Nemotron 70B Instruct HF?

AMD Instinct MI210 can run NVIDIA Llama 3 1 Nemotron 70B Instruct HF at Q4 with an estimated 83 tok/s.

How much VRAM is needed for NVIDIA Llama 3 1 Nemotron 70B Instruct HF on AMD Instinct MI210?

Q4 inference is estimated to need about 35GB VRAM on this page, while AMD Instinct MI210 has 64GB available.

What if AMD Instinct MI210 is not enough for NVIDIA Llama 3 1 Nemotron 70B Instruct HF?

If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.