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Can AMD Instinct MI210 run Microsoft Phi 3 Medium 128K Instruct?

Microsoft Phi 3 Medium 128K Instruct speed on AMD Instinct MI210 and quantization-level VRAM fit.

Runs Q464GB VRAM availableRequires 4GB+

AMD Instinct MI210 meets the minimum VRAM requirement for Q4 inference of Microsoft Phi 3 Medium 128K Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

Buy options for AMD Instinct MI210Best GPU guidesCompare prebuilt systems
Short answer: AMD Instinct MI210 can run Microsoft Phi 3 Medium 128K Instruct at Q4 with an estimated 238 tok/s.
Estimated speed
238 tok/s
VRAM needed
4GB
VRAM headroom
+60GB

What this means for you

AMD Instinct MI210 can run Microsoft Phi 3 Medium 128K Instruct with Q4 quantization. At approximately 238 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 60GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q44GB64GB237.66 tok/s✅ Fits comfortably
Q88GB64GB166.36 tok/s✅ Fits comfortably
FP1616GB64GB90.31 tok/s✅ Fits comfortably

Suitable alternatives

AMD Instinct MI300X
192GB
763.26 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Microsoft Phi 3 Medium 128K Instruct on AMD Instinct MI300X
NVIDIA H200 SXM 141GB
141GB
689.26 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Microsoft Phi 3 Medium 128K Instruct on NVIDIA H200 SXM 141GB
NVIDIA H100 SXM5 80GB
80GB
495.07 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Microsoft Phi 3 Medium 128K Instruct on NVIDIA H100 SXM5 80GB
AMD Instinct MI250X
128GB
477.56 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Microsoft Phi 3 Medium 128K Instruct on AMD Instinct MI250X
NVIDIA H100 PCIe 80GB
80GB
314.26 tok/s
Price: —
Fit note: higher estimated speed than the baseline option.
Check Microsoft Phi 3 Medium 128K Instruct on NVIDIA H100 PCIe 80GB

Compare purchase paths

Direct GPU buy options

Check current pricing links for AMD Instinct MI210 and similar cards.

Open AMD Instinct MI210 buy links →
Curated best GPU guides

Use workload-focused recommendations before committing to a purchase.

Browse best GPU guides →
Prebuilt AI systems

Compare complete systems if you want ready-to-run hardware.

Compare prebuilt systems →

Try before you buy

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More questions

AMD Instinct MI210 buy options & pricingFull guide for Microsoft Phi 3 Medium 128K InstructBest GPU guides for this modelCompare prebuilt local AI systemsBrowse all model + GPU compatibility checksMicrosoft Phi 3 Medium 128K Instruct Q4 requirementsMicrosoft Phi 3 Medium 128K Instruct Q4_K_M requirementsCan AMD Instinct MI300X run Microsoft Phi 3 Medium 128K Instruct?Can NVIDIA H200 SXM 141GB run Microsoft Phi 3 Medium 128K Instruct?Can NVIDIA H100 SXM5 80GB run Microsoft Phi 3 Medium 128K Instruct?

Compatibility FAQ

Can AMD Instinct MI210 run Microsoft Phi 3 Medium 128K Instruct?

AMD Instinct MI210 can run Microsoft Phi 3 Medium 128K Instruct at Q4 with an estimated 238 tok/s.

How much VRAM is needed for Microsoft Phi 3 Medium 128K Instruct on AMD Instinct MI210?

Q4 inference is estimated to need about 4GB VRAM on this page, while AMD Instinct MI210 has 64GB available.

What if AMD Instinct MI210 is not enough for Microsoft Phi 3 Medium 128K Instruct?

If you need more speed or context headroom, compare alternative GPUs below and check higher-tier VRAM options.